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Image Search Results
Journal: PLoS ONE
Article Title: Phospholipase C-Related Catalytically Inactive Protein (PRIP) Regulates Lipolysis in Adipose Tissue by Modulating the Phosphorylation of Hormone-Sensitive Lipase
doi: 10.1371/journal.pone.0100559
Figure Lengend Snippet: (A) COS7 cells cultured with oleic acid with (+) or without (–) adrenaline stimulation (5 µM). Two sets of representative images are shown. The boxed areas of the left image (scale bar: 10 µm) are enlarged in the four right images (scale bar: 5 µm). Five similar images were obtained from three independent experiments. Arrowhead in GFP-PRIP1 and PP2A images indicates an accumulation of each signal at lipid droplet periphery. (B) Intensity profiles along the white lines in the merged images of (A). Compared with unstimulated cells (–Adrn), adrenaline-stimulated cells (+Adrn) exhibit increased fluorescence intensity corresponding to GFP-PRIP1 (green) and PP2A (blue) at the edge of the lipid droplet (red).
Article Snippet:
Techniques: Cell Culture, Fluorescence